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CSSB Newsletter 8
Oliver Grundei, Helmut Dosch, Bärbel Brumme-Bothe, Matthias Wilmanns, Gabriele Heinen-Kljajić, Olaf Scholz . IMAGE Tina Mavric
The CSSB Directorate would like to thank all those who came our grand opening in June. We truly enjoyed celebrating this momentous occasion with you.
In November, we are looking forward to welcoming the international scientific community to our Opening Symposium and to opening our doors to the local community during the Hamburg Night of Sciences. Learn more about our upcoming events and most recent scientific publications below.
IMAGE: Tina Mavric
CSSB CELEBRATES ITS GRAND OPENING
On 29 June, CSSB celebrated its grand opening on the DESY Campus in Hamburg. With a view of the new building, over 500 guests applauded as Helmut Dosch, Chairman of the DESY Board of Directors, presented Matthias Wilmanns, CSSB Scientific Director, and Dirk Heinz, Chairman of CSSB Council with a ceremonial key thus marking the official begin of scientific research in the new CSSB building.
In September, three electron cryo microscopes were delivered and are currently being installed in the basement of the CSSB building. The two remaining microscopes will be delivered later this year. Click on the link below for more information about the advantages of electron cryo microscopy and to discover how the microscopes will be used at CSSB.
CSSB was honoured to host a delegation of UN ambassadors from sub-Saharan African countries on 12 October. The ambassadors enjoyed a presentation by Chris Meier followed by a tour of the CSSB building and the neighbouring PETRA III beamlines. CSSB was just one stop on the ambassadors' week-long visit organized by the Guest Programme of the Federal Republic of Germany on the topic of global engagement in the health sector.
CSSB OPENING SYMPOSIUM
The CSSB Opening Symposium: Frontiers in Structural Systems Biology of Host-Pathogen Interactions will take place in the new CSSB building from 13-15 November 2017.
Abstract submission deadline is 20 October and the registration deadline is 31 October.
IMAGE: David S. Goodsell, the Scripps Research Institute
CSSB IS PART OF DESY DAY
CSSB will be participating in DESY DAY on 4 November from 12:00-24:00. Stop by to meet our scientists and learn about their research. Activities in our building include presentations of research, software demos, and guided tours of our microscope facilities as well as games and crafts for children.
A team of researchers from Germany and the Netherlands have determined the structure of an amyloid fibril with previously unachieved resolution. The fibrils of the body’s own amyloid beta (Aβ) protein are the main constituent of Alzheimer’s disease related and characteristic pathological protein deposits in the brain. CSSB Group Leader, Jörg Labahn, was involved in the elucidation of the atomic-level three-dimensional structure.
IMAGE: (C)Forschungszentrum Jülich / HHU Düsseldorf / Gunnar Schröder
NEW ROLE FOR A PROTEIN COMPLEX
Martin Hällberg’s group studies the initial processing around mitochondrial tRNAs. The Hällberg group found that two of the proteins from the RNase P complex, MRPP1 and MRPP2, surprisingly remained bound to the tRNA even after the initial 5´-processing. Even more surpisingly, the MRPP1/2 complex was also necessary for ELAC2 to cut in the 3´-end of the tRNA genes.