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cryo-EM

CRYO-EM MULTI-USER FACILITY

In electron cryo-microscopy, samples are first flash-frozen and then studied under an electron microscope. As result of this flash freezing the molecular structure, even at the atomic level, is preserved in its natural form and can be studied in a state that is structurally unchanged. Based on a number of recent technical advances, particularly in the area of novel detectors, electron cryo-microscopy has developed into an essential method in structural biology research. It is one of the most revolutionary microscopic approaches in science and it has made the observation of molecular life in its native state possible.

With the help of five electron cryo-microscopes, scientists will study the complex molecular structures and function of pathogens as well as their interactions with host cell components such as proteins and membranes.

Drucker