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Jörg Labahn

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X-Ray Crystallography

"CSSB offers an attractive combination of biophysical methods for the structural characterization of proteins. Its dedication to targets which are directly relevant for human health, confers a healthy purpose"

Jörg Labahn, CSSB Group Leader


Collaborative Research in Infection Biology

Together with other CSSB researchers his group investigates proteins which are relevant in infection biology. Particularly CSSB‘s combined expertise in imaging and diffraction studies will enhance research opportunities in Membrane Protein Complexes.

A major goal for the next years is to analyze membrane protein structures. In particular, Labahn focuses on developing an approach which allows collecting in-situ diffraction data from crystals obtained with his in-meso-phase crystallization method.

Newest Publications

Expression, purification, and preliminary characterization of humanpresenilin-2
Yang G, Kun K, Kubicek J, Labahn JProcess Biochem. 2017 Sep 12 doi: 10.1016/j.procbio.2017.09.012. [Epub
ahead of print]

Fibril structure of amyloid-ß(1-42) by cryoelectron microscopy.
Gremer L, Schölzel D, Schenk C, Reinartz E, Labahn J, Ravelli RBG, Tusche M, Lopez-Iglesias C, Hoyer W, Heise H, Willbold D, Schröder GF.
Science. 2017 Sep 7. doi: 10.1126/science.aao2825. [Epub ahead of print]

Structural basis for the regulatory interactions of proapoptotic Par-4.
Tiruttani Subhramanyam UK, Kubicek J, Eidhoff UB, Labahn J.
Cell Death Differ. 2017 Sep;24(9):1540-1547. doi: 10.1038/cdd.2017.76. Epub 2017 Jun 16.

High-efficient production and biophysical characterisation of nicastrin and its interaction with APPC100.
Yu K, Yang G, Labahn J.
Sci Rep. 2017 Mar 9;7:44297. doi: 10.1038/srep44297.



Picture: © Marta Mayer
Drucker