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CSSB Seminar Series - MARTIN PILHOFER

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Abstract: 

We are intrigued by the many ways bacteria interact with other cells. Our goal is to establish mechanistic models of macromolecular machines mediating these cell-​​cell interactions. We integrate information from the molecular to the cellular and intercellular scale, by combining our key technique cryo-​​electron tomography (cryoET) with other imaging techniques and functional assays. Our main focus are bacterial contractile injection systems and I will report our latest progress on the discovery and characterization of novel systems.