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CSSB: Newsletter 20

So far, 2023 has been a busy and exciting year at CSSB. In May, we held our 3rd international symposium with over 100 participants. Our second scientific evaluation with external evaluators took place in June. We braved high winds and stormy weather in July for our second CSSB All Retreat in Wedel.

We are happy to welcome two new group leaders to CSSB. Meytal Landau's group will be investigating microbial amyloid fibrils, which serve as key "weapons" making infections more aggressive. Caroline Barisch's group focuses on decipering the molecular mechanisms by which pathogenic mycobacteria remodel, acquire, import and utilise lipids from their host to support infection.

On October 4 at 19:00, we will be hosting a panel discussion together with the Academy of Sciences and Humanities in Hamburg. "Biofilms: The Sticky Science of Microbial Cities will explore how bacterial communities impact our health and environment. We hope you will join us for this event!

CSSB NEWS

IMAGE: Melissa Prass

RESIST visits CSSB

On August 29, researchers from CSSB gave a warm welcome to seven members of the Cluster of Excellence RESIST who came to visit.

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SPIDoc's - The next generation MS SPIDoc's

Professor Charlotte Uetrecht (CSSB, DESY, LIV and Uni Siegen) will coordinate "SPIDoc's - The next generation MS SPIDoc's" a new Doctoral Network funded within the Marie Sklodowska-Curie Actions. The University of Siegen and CSBB in Hamburg will be central locations for SPIDoc's.

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IMAGE: Catalin Bunduc

Catalin Bunduc receives a Veni grant

Microbiologist Catalin Bunduc from the Marlovits group receives a Veni grant for his research into tuberculosis. With his research he wants to understand how the tuberculosis bacterium infects us and thus open the door to new therapeutics against tuberculosis.

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IMAGE: DESY, Georg Wendt

German Federal Health Minister Karl Lauterbach visits DESY

Prof. Karl Lauterbach, the German Federal Health Minister, visited the DESY and CSSB on 30 June 2023.

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IMAGE: Paulista / Adobe Stock

VISION: new DFG Research Training Group

Viruses can not only make us humans sick, but in the worst case they can also shake up social and economic structures. The Corona pandemic has clearly demonstrated this lesson to us. For future pandemics, the response time for the development of antiviral drugs and vaccines against viral infections must be improved. This requires optimal training of future virologists. To this end, the German Research Foundation has now approved a new Research Training Group "VISualization and imaging of virus InfectION (VISION)."

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IMAGE: Tina Mavric

CSSB's 3rd international symposium

Over 100 participants attended CSSB's 3rd international symposium "Charting the landscape of infection: From entry to exit" held from May 3-5, 2023. The symposium focused on the biology of infections and highlighted different key cellular processes leading to pathogen proliferation. The symposium featured 11 invited speakers and 20 abstract speakers and provided the participants with a multitude of opportunities for networking and scientific exchange.

Meytal Landau wins EU grant to study amyloids

Structural biologist Meytal Landau has been awarded two million euros by the EU to investigate microbial amyloid proteins. Amyloids are fibrous proteins that are of interest in various areas of medicine. Landau's ERC Consolidator Grant from the European Research Council (ERC) will last five years and will help build a team at the Centre for Structural and Systems Biology (CSSB) on the DESY campus that will involve DESY, the Hamburg branch of the European Molecular Biology Laboratory (EMBL), and the University Hospital Hamburg-Eppendorf (UKE).

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UPCOMING CSSB EVENTS

PANEL DISCUSSION

How do biofilms form? How does science study their diversity? Are there "good" and "bad" biofilms? What could we learn from them? Could biofilms even help us on the way to creating a sustainable society? These questions and more will be answered during the panel discussion on October 4 at 19:00. Organized by CSSB and the Academy of Sciences and Humanities in Hamburg the panel discussion will take place in English. Invited speakers are Prof. Dr. Meytal Landau, Prof. Dr. med. Holger Rohde, Prof. Dr. Holger Sondermann and Prof. Dr. Fitnat Yildiz.

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CSSB Seminars

Upcoming CSSB Seminars:

October 5: Fitnat Yildiz
November 8: Ilaria Ferlenghi
December 7: Erica Ollmann Saphire

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IMAGE: Tina Mavric

Hamburg Life Science Seminar Series

This new seminar series, hosted by EMBL and CSSB, looks to strengthen Hamburg's growing life science community and provide our PhD students and postdoctoral researchers with exciting new networking opportunities.

November 10: Han Remaut
November 24: Pascale Cossart

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SCIENTIFIC NEWS

PickYOLO

The Marlovits group and collaborators at Helmholtz Imaging/DESY have developed PickYOLO, an ultrafast particle finder for cryo electron tomograms.

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IMAGE: Marini G et al. (2023) Nat Commun. 14(1):417

A Powerful Insecticidal Protein

CSSB scientist Guendalina Marini, from the Topf group and former member of the Saibil group (Birkbeck, London) in collaboration with the company Corteva Agriscience, has recently demonstrated that a promising insecticidal PFP, Mpf2Ba1, isolated from bacterium Pseudomonas monteilii, shows potent control against corn rootworm through a different site of action than Bt proteins.

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IMAGE: Bruederlin M et al. Nat Commun 14, 1002

How do molecular machines pass the ball?

CSSB researcher Dr. Badri N. Dubey (DESY) from the Sondermann group, together with collaborators from Biozentrum, University of Basel, Switzerland, has revealed the molecular mechanism by which proteins pass a signal via a multi-step relay in a signaling pathway.

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Contact Information

Centre for Structural Systems Biology (CSSB)
c/o DESY, Building 15
Notkestr. 85
22607 Hamburg
Germany
E-mail: info@cssb-hamburg.de

To find out more about CSSB please visit our website:
www.cssb-hamburg.de
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