We use cutting edge technologies and methods to investigate how pathogens infect humans
The CSSB group of Michael Kolbe focuses on understanding the molecular mechanisms of the T3SS. In a recent publication in PLoS Pathogens, the Kolbe group presented the first cryo-EM Structure of the isolated Shigella needle complex which reveals new insights into the architecture and function of this essential virulence factor. Read more
Save the date for the CSSB Symposium 2020 which will take place from 2-4 December 2020. The symposium entitled "Charting the landscape of infection: From entry to exit" will focus on a cross-disciplinary interrogation of the molecular mechanism of human infections. Registration information will be available soon. Read more
Our facility is currently the most ad- vanced centre for cryoEM in the north of Germany housing five electron microscopes: two Titan Krios instruments equipped with phase plates, energy filters, K3 and Falcon 3 direct detectors, a Talos Arctica with a phase plate and a Falcon 3 direct detector, a Talos L120C and an Aquilos FIB cryo-SEM for preparing lamellae of thick samples, such as vitrified cells or crystals. Your responsibilities would be comprised of 85% equipment set-up and operation, equipment maintenance, 15% user-training and assistance. Read more
We are ten research partners from Northern Germany. We endeavor to become a leading international research centre in the city of Hamburg.
Empowering the next generation of scientists is an integral element of the CSSB’s mission. We offer you privileged access to research infrastructures.
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